Stuffed Artichoke Casserole….easy to make and super delicious...a fitting tribute to the Italian immigrants that contributed so much to the New Orleans and Louisiana culture. Let’s see how to make this no-angst recipe...you’ll love it and want to make it time and time again.

Where it all begins...Stuffed artichokes….unbelievably delicious. One of the many contributions to our culture for which we can thank our Italian immigrant ancestors. There’s a certain ritualistic element in devouring one of these treasures, scraping the filling and some artichoke meat off each artichoke leaf, piling up the eaten leaves. It's fun, messy and very delicious. It's also pretty labor intensive to properly stuff one of these girls, although the distinctive and satisfying flavor is well worth the effort. But, if you don't have the time or patience to tackle that chore, Sweet Daddy D has come up with a simple, no-angst version which captures the unique flavor combination in a casserole.
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Here’s What You Need
Artichokes are at the heart of this dish...do you see what I did there? I couldn't resist. Fresh artichokes are great, but very time consuming to prep. The thing that makes this casserole so simple and no-angst is using a good quality canned artichoke hearts. You can get them anytime of year and keep them in the pantry until you're ready to enjoy this Italian masterpiece. I always use the ones packed in brine and not marinaded, although the marinaded ones would probably work fine since we are also using some good olive oil and Italian herbs. Use the quartered ones-half will be chopped up fine, but the other half will be used whole (well, at least a whole quarter)! Fresh garlic, seasoned breadcrumbs, Romano Cheese and lemons define the flavor of this dish. The Herb and Spice Blend also leans towards Italian flavors-dried oregano, basil and thyme, along with kosher salt and ground black pepper plus a little chopped fresh parsley for some brightness. It’s simple and all ingredients add something important to the flavor profile. Beer adds something important to the chef’s profile.
Here’s What You Do
First...you have a beer. Maybe to spice things up, try an Italian Beer, maybe a Birra Moretti La Rossa-I think that would go really well while you are preparing this. (You should know that if you buy from Saucey, I will make a modest commission). Your Mise En Place practice is simple for this one. Have a beer, read the recipe, make sure you have everything, preheat the oven to 400 degrees, then prep all the ingredients.
Mise en Place
Drain the artichoke hearts, take half and chop them fine. Leave the other draining in a colander. Measure all the Herbs and Spices and place them in a ramekin. I always like to leave the salt out until I taste it later. The lemons really contribute. Zest one lemon, then squeeze the juice in a ramekin. Thinly slice the second lemon and set all that aside. Chop the garlic cloves and the parsley-fine or course, whichever is your preference. Finally, measure out the olive oil, breadcrumbs and Romano Cheese.
Combine all ingredients
Couldn't be simpler. In a large bowl add the chopped artichoke hearts, the breadcrumbs, Romano cheese, Herbs and Spices, garlic, parsley, lemon zest and juice. Mix them all together, then add the whole artichoke quarters-it's just makes it slightly easier to mix if you add these last.
Add the olive oil
Once all the dry ingredients and lemon juice are mixed together well, add ¼ cup of olive oil and mix it all in. This will be absorbed by the breadcrumbs and cheese but you want it to be moist and sticking together when you make a little test ball.
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Place it all in a baking dish
Coat an 8 X 12 baking dish lightly with olive oil, then pour everything in and smooth it out so it's all the same thickness. How’s your beer?
Finish it for the oven, cover with aluminum foil
Drizzle a little more olive oil all over the casserole, then sprinkle more Romano Cheese on top. Place the lemon slices on top in a single layer. Cover the whole thing tightly with aluminum foil.
Place in the 400 degree oven
It will bake for a total of 30 to 35 minutes. Leave it covered with foil for the first 25 minutes-this will encourage a little steaming action and will help keep it moist. Take the foil off and stick it back in for 5 to 10 minutes, until its just starting to brown.
There you have it, simple as that. This casserole has such a distinctive flavor-like walking into Central Grocery on Decatur down in the Quarter...unforgettable and feels like home.
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Yeah You Right!
Stuffed Artichoke Casserole
Here's What You Need
- ¼ cup olive oil plus some for drizzling on top
- 2 lemons
- lemon zest
- 6 cloves garlic
- 28 ounces artichoke hearts-quartered
- 1 cup seasoned bread crumbs
- ½ cup grated Romano cheese plus some for the top
- 2 tablespoons parsley chopped
Herb and Spice Blend
- 1 teaspoon dry oregano
- 1 teaspoon dry basil
- ½ teaspoon dry thyme
- ½ teaspoon Black pepper
- Kosher salt to taste
Here's What You Do
- Preheat oven to 400 degrees.
- Chop half of the artichoke hearts into fine pieces, set aside.
- Zest and juice one lemon; slice the other lemon.
- Chop the garlic and parsley.
- Combine the chopped artichoke, breadcrumbs, garlic, Romano Cheese, parsley, lemon zest, lemon juice and the Herb and Spice Blend together in a bowl.
- Add in the whole artichoke quarters, mix well.
- Add in ¼ cup of the olive oil and mix well.
- Place into a greased oven-safe casserole dish.
- Drizzle more olive oil on top-about 2 tablespoons.
- Sprinkle Romano Cheese on the top
- Place the lemon slices on top.
- Cover with aluminum foil and bake for 25 minutes in 400 degree oven.
- Remove the aluminum foil and place back in the oven for 5 to 10 minutes
Helen Joffe
Five stars! Super easy and delicious!
Sweet Daddy D
Thanks, Helen! So glad you liked it. I appreciate the comments!!
AF
Hi, I just want to clarify that I measure out the 28 ounces of artichokes after draining them? I can't wait to make this??? My step mother made something similar that was scrumptious. Thank you!
Sweet Daddy D
That is correct, Anna. Drain the hearts before measuring. Thanks for reaching out, I hope you enjoy the recipe.
Carol
Loved the recipe , my family ate the whole pan , next time I will only use the lemon zest I’m not big on lemon ,, but it was delicious
Sweet Daddy D
Thanks, Carol. I'm so glad your family liked it. Anchovies sound pretty good, they give such a nice briny flavor but cook away to nothing. I appreciate you reaching out to me.
Terry
Happy Thanksgiving! I only found your site last night, and I'm so glad that I did! We're going to dinner with friends so I'm not cooking today, but I definitely will be making this for Christmas! Just a quick question - do you use light olive oil or extra virgin in this casserole? Thanks! I'm looking forward to exploring your other recipes!
Sweet Daddy D
Hi, Terry, so glad you visited and Happy Thanksgiving to you and yours. I use Extra Virgin Olive Oil, but I’m sure light would work. I find the EVOO has a little more depth of flavor, but in this recipe I think either would work.
Shana
OMG I'm so excited about this dish......hopefully there will be some left to bake , as I have been picking at it....so darn tasty. Making it today for thanksgiving. Thank you for the recipe....I'll let yall know how everyone likes it. HAPPY THANKSGIVING!
Sweet Daddy D
Happy Thanksgiving, Shana. Enjoy!
Regina Stein
Can I bake it the day before, put it in the refrigerator overnight and then reheat it? If so, what temperature and how long?
Sweet Daddy D
Hey, Regina. Yes, you can do that. Make sure you bring it back to room temperature and then cover it airtight with plastic wrap. When you want to bake it, take it out the fridge about an hour before and then reheat at 350 degrees for about 20 minutes, probably best to cover with aluminum foil. HOWEVER, why don't you just get it all together in the baking dish and refrigerate before you bake it? Then take it out 1 hour before and bake at 350 for 30 minutes or so. I think it would be better that way and save you a little time. Thanks for reaching out.
Regina Stein
Thank you for the suggestion and hope you have a Happy Thanksgiving! ? ? ? ☕
Sweet Daddy D
Happy Thanksgiving, Regina!
Janet Anne
Sweet Daddy,
That is what i am going to do..Thanks for info. Happy Thanksgiving!
Sweet Daddy D
Great, have a Happy Thanksgiving, Janet.
Shaina
This may be a stupid question, but I purchased two 12 oz jars of artichoke hearts, but it says they are only 8 oz once drained. Do you recommend going off the 12 oz or 8 oz description? Should I buy another jar?
Thanks! and so excited to make this for Thanksgiving!
Sweet Daddy D
Hi Shaina, thanks for the question. I would use the 8-ounce measurement because you want to drain the jars or it would likely be too much liquid. I'm glad you're going to try my recipe, let me know how it turns out.
Roe fruci
When I saw this I was like yeah I gotta try this I love artichokes I just dont like lemon tyme so I will not add I am trying it now and I added bacon crispy and some mozzarella cheese. .so I am waiting for it to cook
Sweet Daddy D
Roe-that sounds fabulous. I can't wait to hear how it turns out. Thanks for reaching out!
Denys Meade
I was so excited to find this recipe! I am making it for Thanksgiving. Italian girl here from Boston. I will omit the lemon as I don’t like the taste of them. I know, it’s sad but true........
Sweet Daddy D
Make it yours, Denys! Thanks for reaching out...ENJOY!
Marie
I made your casserole last night and it was awesome! Everyone loved it. I will certainly make it again soon. It called for 8 x 12 pan but I used an 8 x 8 because I think it would’ve been too skinny. Thank you for sharing!
Sweet Daddy D
Yeah You Right, Marie! Thanks for trying the recipe and I'm excited you loved it. Thanks for reaching out!
Hoonay
SO quick and easy to make that I can myself having this as a quick and easy side on a regular basis.
I used one lemon--cut five slices for top, squeezed the rest, and the lemon was kind of the first flavor I tasted... I thought it was great, but I might scale back a bit on the lemon when making it again.
And I can't imagine what 6 cloves of garlic would have tasted like, I used maybe 4, and it was definitely a presence. Might scale that back a bit, too.
Sweet Daddy D
Great Hoonay! I am so glad you tried my recipe and think it's wonderful that you made some adjustments to fit your personal preferences. That's what it's all about! Thanks for the comment.
Jennifer
This is so fantastic!!!
Sweet Daddy D
Thanks again, Jennifer, much appreciated!
Jennifer
This is so yummy! Love it.
Sweet Daddy D
Yeah You Right, Jennifer. Thank you!
Tony
How important is the oregano, thyme and basil I never use it when stuffing by artichoke.
Sweet Daddy D
Hey, Tony. Those herbs are only important if you like them. If your preferred way to make stuffed artichoke is without those flavors then you should skip them. To me, the garlic, lemon and Romano cheese are the real flavor driver in this recipe. Enjoy and thanks for reaching out!
MaryAnn
This sounds so good I'm making it for Thanksgiving. Can I mix it up the night before, refrigerate in the baking dish, then bake the next day? Or will that let the breadcrumbs get too soggy? Thank you.
Sweet Daddy D
That should be fine, MaryAnn. Make sure to cover it tightly (airtight) and let it get to room temperature before you bake it. Thanks for reaching out, I hope you enjoy it!
Saf0723
Thanks for the recipe ! Definitely adding this to my Thanksgiving menu this year. I find dried basil doesn’t have any flavor. And fresh looses its flavor when cooked at high temps .So What other spices would you recommend besides basil and Tyne ?
Sweet Daddy D
Hey Sheryl, I'd probably just increase the oregano but some good substitutes may be savory or marjoram. I also think sage, tarragon and rosemary may fit this recipe but these may have the tendency to be a little overpowering if too much is used-same as the thyme. Whatever herbs you use, make sure they are fresh-especially the dried herbs. If your dried basil is flavorless and has no fragrance, try another brand or get some fresh basil and dry it out to use later. Thanks for reaching out, I'd love to know how it turns out.
Karen D Moulton
This looks delicious.
Is it an entree or side dish?
Sweet Daddy D
Hey, Karen. I've always looked at this as a side dish. However, I suppose it could be considered an entree for a vegetarian diet depending on one's feelings about the cheese. Depending upon the brand, Romano cheese can be vegetarian or non-vegetarian. Thanks for the question!
Jacqueline Endlich
Why why why didnt I think of this? You use our family recipe so I am sure its going to be great. Thank you for this shortcut!
Sweet Daddy D
That's the beauty of this recipe...awesome, traditional flavor in a simple form. Enjoy and thanks for reaching out, Jacqueline!
Karen
Could I use frozen artichoke hearts,thawed. Or would that change the flavor as they wouldn't have soaked in brine. Trader Joe's sells frozen ones.
Sweet Daddy D
Karen, frozen work well, I've used them myself. The idea with the brined hearts is that it doesn't really add any flavor. The brine is mostly water as opposed to the marinated hearts which are in olive oil and spices and have a flavor beyond the hearts. Delicious, but still flavored. Good luck and thanks for reaching out.
Elizabeth Sinnott
Delicious! I'm from New Orleans, but live in Kansas City, MO and always looking for my southern Louisiana recipes!
Sweet Daddy D
Thanks, Elizabeth!